Comments on: 7 Uridine Benefits + Sources, Side Effects, Stacks & Dosage

By: Kim

Kim — Mon, 18 Nov 2019 10:29:17 +0000

In reply to susan.

Hi Susan, thanks for your comment. We don’t answer personal health questions in the comments section for privacy reasons. If you’re looking to get answers from Joe, please join SelfHacked VIP at https://selfhacked.lpages.co/selfhackedvip/. Feel free to get in touch with us with any questions about how our VIP members area works at [email protected].

By: susan

susan — Sun, 17 Nov 2019 19:26:52 +0000

Hi,

I recently started taking uridine 300mg one-two times a day. I also take NAC 1800-2400mg a day. I added acetyl l-carnitine, b complex and omega 3 to subvert any problematic long term effects of uridine. I feel much better and my depressive symptoms are almost gone. It’s been about 3 weeks now, taking this cocktail. My questions is how long can I take uridine, safely? and shd I take one 300mg capsule w lion’s mane or stack w/another nootroopic to protect against long term adverse effects or switch it off with another nootropic or stack if so I don’t create any medical problems? If that’s the case stack with which nootropic or switch to which nootropic and when to switch and switch back? Thanks so much. These answers are difficult to find.

By: Todd

Todd — Wed, 04 Sep 2019 19:57:59 +0000

According to this publication here:
http://molpharm.aspetjournals.org/content/molpharm/88/2/220.full.pdf
“At P2Y2 and P2Y4 receptors, UMP and UDP are inactive, but some of their analogs activate these receptors as well as UMP analogs at P2Y6R”

So, regarding Health Concerns 2) Heart Scarring. Looks like it is only an issue when consuming UTP.

By: Marieke

Marieke — Tue, 24 Jul 2018 15:44:04 +0000

Hi Joseph , would uridine be helpfull for a DRD1 and DRD2 gene mutation ? If not what other supplement(s) do you reccomend for those mutations ?

By: Kevin

Kevin — Mon, 09 Apr 2018 21:30:10 +0000

I see you pointed toward several genes I can checkout if I have 23 and me…but what exactly am I looking for when I look at these?

By: douglas Gerard

douglas Gerard — Mon, 25 Sep 2017 03:44:08 +0000

I would suggest you get your uridine from natural sources like beer or vegetables and NOT pills…more and more otc vitamin supplements are being blamed for numerous health problems when taken in excess dosage

By: Tom

Tom — Mon, 04 Sep 2017 09:17:02 +0000

So uridine will get the brain working right, but might cause cancer, although that scary proposition is mostly a hypothesis in need of more testing at this point. Sometimes facts as they are presently known are disappointingly ambiguous when it comes to decisions about what to use or not to use. It seems uridine exists in that no man’s land at this time.

By: eddie

eddie — Thu, 20 Apr 2017 20:29:24 +0000

would cdp choline or alpha gpc be a better option ??

By: Jessie

Jessie — Sun, 29 Jan 2017 15:33:55 +0000

In reply to Joseph M. Cohen. This is the most comprehensively researched and referenced article I could find online about Uridine UMP. Most blog articles are simply anecdotal or just repeat what they've read on other sites without any scientific references. This article is a thorough overview of uridine in the literature, and while each statement is not necessarily analyzed here, all statements are referenced to lead you into your own investigation. Not at all disappointing.

By: Garry

Garry — Sat, 14 Jan 2017 23:47:06 +0000

What is the difference between pharmacological use of uridine which increases risk of cancer versus dietary supplementation which reduces risk of cancer. Uridine monophosphate seems to have numerous benefits which I would like to explore, but I do not want to increase the risk of cancer. How can Uridine monophospate be taken without increasing risk of cancer? ie. supplementally. Is this by keeping dosage below a certain level or by combining with other nutrients? Thank you.

By: John jihn

John jihn — Sun, 28 Aug 2016 23:00:38 +0000

In reply to John jihn. I agree to some extend, but they are still helpful... They give a good overall overview but they lack in the aspect of getting a deeper understanding of the substance and how it works.. I feel like they should be some kind of sidebar material.. These articles are also less likely to be affected by tunnel vision..

By: John jihn

John jihn — Sun, 28 Aug 2016 22:55:05 +0000

In reply to Thepractice. I agree

By: Joseph M. Cohen

Joseph M. Cohen — Sat, 25 Jun 2016 22:27:17 +0000

In reply to Thepractice. Why are they disappointing? I'm trying to build up a supplement database.

By: Thepractice

Thepractice — Sat, 25 Jun 2016 09:54:40 +0000

These “21 Benefits of Supplement X” and “All you need to know about supplement Y” articles are dissapointing me. Seem to be for SEO purposes.

By: Graeme

Graeme — Fri, 24 Jun 2016 09:52:03 +0000

Uridine may cause cancer – http://www.sciencedirect.com/science/article/pii/S0304383516000197